Bilirubin direkt (konjugiertes Bilirubin)
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Fragen und Antworten zu Bilirubin direkt
What is the respective laboratory value?
Direct bilirubin is the water-soluble form of bilirubin that is formed in the liver through conjugation. It is excreted into the bile ducts and serves as a marker for diseases of the liver or bile ducts.
For whom is such a test to be considered?
A test for direct bilirubin is recommended for: • People with symptoms such as jaundice, itching or abdominal pain • Patients with suspected bile duct obstruction or biliary tract diseases • Monitoring of patients with liver or gallbladder diseases • Clarification of unclear increases in total bilirubin
What is it used for?
The test helps to distinguish the cause of increased total bilirubin. Direct bilirubin is increased in diseases that are associated with impaired bile flow or liver dysfunction.
What can be inferred from that?
An elevated direct bilirubin level often indicates: • Bile duct obstruction (cholestasis) due to gallstones or tumors • Liver diseases such as hepatitis or cirrhosis • Biliary atresia in newborns Symptoms may include: • Jaundice • Dark urine and light-colored stool • Itching due to bile acids
What is the ideal time for a test?
The testing can be carried out at any time of the day.
Particularly interesting?
A directly elevated direct bilirubin usually indicates a disrupted bile flow, whereas an increase in indirect bilirubin is often associated with hemolysis. Direct bilirubin values are particularly helpful in clarifying biliary tract diseases. Chronic diseases such as primary sclerosing cholangitis can also lead to elevated values.