Harnstoff

Urea is an end product of protein metabolism and is produced in the liver. The laboratory value measures the concentration of urea in the blood and is used to assess kidney function and protein metabolism.

A urea test is recommended for: • People with symptoms such as fatigue, loss of appetite or swelling (indication of kidney disease) • Patients with suspected renal insufficiency or urinary tract problems • Monitoring of patients with chronic kidney disease or dialysis patients • Clarification of disorders of protein metabolism

The test serves the diagnosis and monitoring of kidney diseases and the assessment of protein metabolism. It helps to identify causes of increased or reduced urea.

Here is the translation: An elevated urea level can indicate: • Kidney failure or impaired kidney function • Dehydration (reduced urea excretion) • Excessive protein intake or breakdown (e.g. due to injuries, burns) A low value indicates: • Liver diseases (reduced production of urea) • Malnutrition or low protein intake Symptoms of abnormal values can include: • Swelling, nausea or fatigue with elevated urea • Loss of appetite or weight loss with low values

The testing can be carried out at any time of the day and is independent of food intake.

• Urea alone is not enough to assess kidney function; cystatin C and uric acid should be measured as a supplement. • An elevated urea value can also occur with dehydration and must be interpreted in the context of fluid balance. • Medications such as corticosteroids or diuretics can affect the urea level.