Iron

Iron is a trace element that is essential for the formation of hemoglobin and the transport of oxygen in the blood. The laboratory value measures the concentration of iron in the serum and is used to assess iron metabolism.

An iron test is recommended for: • People with symptoms such as fatigue, paleness or shortness of breath (indication of anemia) • Patients with suspected iron deficiency or iron overload (e.g. hemochromatosis) • Monitoring of patients with chronic blood loss (e.g. in gastrointestinal diseases) • Women with heavy menstruation or during pregnancy

The test serves to diagnose iron deficiency anemia, iron overload, or to clarify symptoms that indicate disturbances in iron metabolism. It also helps to monitor the success of iron therapy.

A low iron value indicates: • Iron deficiency due to blood loss or insufficient intake • Chronic inflammation that affects iron metabolism A high iron value can be caused by: • Hemochromatosis (genetic iron overload) • Blood transfusions or iron-containing medications Symptoms of iron deficiency: • Fatigue, paleness, brittle nails • Shortness of breath with exertion

The testing can be carried out at any time of the day and is independent of food intake.

The iron value alone is often not enough; ferritin (iron storage) and transferrin (iron transport) should also be determined. Chronic diseases can alter iron metabolism without a true deficiency being present (anemia of chronic disease). Overdosing on iron preparations can be toxic and should be avoided.