Uric acid+D3

Uric acid is a breakdown product of purines, which are formed through the breakdown of cell nuclei or diet. The laboratory value measures the concentration of uric acid in the blood and is used to assess purine metabolism and kidney function.

A uric acid test is recommended for: • People with symptoms of gout (e.g. painful, swollen joints) • Patients with kidney disease or impaired kidney function • Monitoring of patients undergoing chemotherapy or radiation therapy (due to increased cell breakdown) • Persons suspected of having metabolic syndrome or hyperuricemia

The test serves the diagnosis of gout, the monitoring of purine metabolism, and the assessment of kidney function. It is also used to estimate the risk of uric acid stones in the kidneys.

An elevated uric acid level (hyperuricemia) indicates: • Gout (uric acid crystals in the joints) • Kidney stones due to uric acid deposits • Increased cell breakdown (e.g. due to cancer treatment) A low value rarely has clinical significance, but can occur with certain liver diseases or medication. Symptoms of elevated levels can include: • Acute joint pain, especially in the big toe (gout attack) • Swelling and redness of the joints

The testing can be carried out at any time of the day and is independent of food intake.

• Chronically elevated uric acid levels without symptoms are referred to as asymptomatic hyperuricemia, which poses a long-term risk of gout or kidney disease. • Alcohol consumption and purine-rich foods (e.g., meat, seafood) increase uric acid levels. • Medications such as diuretics or chemotherapeutics can affect the values.

Vitamin D is a fat-soluble vitamin that is produced in the skin through sun exposure and is also obtained through the diet. The laboratory value measures the concentration of vitamin D to assess the body's supply status.

A vitamin D test is recommended for: People with muscle weakness or bone pain Persons with chronic fatigue or exhaustion People with low sun exposure (e.g. office work, living in northern regions) People with dark skin (reduced vitamin D production) Older people (declining skin synthesis) Pregnant and breastfeeding women Persons with osteoporosis or chronic diseases (e.g. autoimmune diseases, diabetes)

The test serves to detect a vitamin D deficiency or an overdose. Vitamin D is essential for calcium and phosphate metabolism and contributes to bone health, muscle strength, and immune defense. A deficiency can increase the risk of osteoporosis, infections, and chronic diseases.

A low value indicates a deficiency that can be due to insufficient sun exposure, improper nutrition, or diseases such as malabsorption disorders. Symptoms of a deficiency are: Bone and muscle pain Muscle weakness and risk of falls Increased risk of infections An elevated value, usually due to excessive intake of vitamin D supplements, can lead to nausea, confusion, and calcium deposits in organs.

A test is possible all year round, but is particularly useful in winter and spring when the body's own stores are depleted due to lack of sun exposure. Persons with risk factors or symptoms of deficiency should be tested regularly. The test can be carried out at any time of the day and is independent of food intake.

Vitamin D is taken in two forms: D2 (ergocalciferol) from plant sources and D3 (cholecalciferol) from animal sources or through sunlight. D3 is better utilized by the body. Supplementation should be done under medical supervision, as overdosing can lead to health problems. The body's own production of vitamin D depends on factors such as skin type, age, geographic location, and season.