Folic acid, also known as folate or vitamin B9, is a vital nutrient that is required for cell division and proliferation, and plays an important role, together with vitamin B12, in the formation of red blood cells. A deficiency of folic acid can be particularly dangerous during pregnancy and can lead to birth defects in the unborn child. However, symptoms can also occur outside of pregnancy due to a deficiency.
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Vitamin B9, also known as folate or folic acid, is a water-soluble vitamin that plays a crucial role in cell division, DNA synthesis, and blood formation. The laboratory value measures the concentration of folate in the serum.
A Folat test is particularly suitable for: Pregnant women or women who wish to have children (to prevent neural tube defects in the fetus) People with signs of anemia (e.g. fatigue, paleness) Persons with chronic intestinal diseases (e.g. celiac disease, Crohn's disease) Alcoholics or people with inadequate nutrition Older people suspected of nutrient deficiency
The test helps to diagnose a folate deficiency, which is often the cause of megaloblastic anemia. This form of anemia leads to an enlargement of the red blood cells and reduced cell division ability. Furthermore, vitamin B9 is essential for the prevention of neural tube defects during pregnancy.
A low folate value indicates inadequate intake or absorption disorder. A deficiency can show the following symptoms: Fatigue and weakness Concentration difficulties Paleness and shortness of breath Increased risk of malformations in the unborn child (e.g. spina bifida) An elevated value is rare, but can occur due to excessive supplementation.
The testing should be carried out in case of symptoms such as anemia or chronic fatigue. Women with a desire to have children or pregnant women should have their folic acid status checked early, ideally before conception or at the latest in the first trimester. The testing can be carried out at any time of the day and is independent of food intake.
Folic acid is the synthetic form of folate and is better absorbed by the body, which is why it is often used in dietary supplements and fortified foods. Chronic folate deficiency can lead to an increased homocysteine level, which is a risk factor for cardiovascular diseases. Alcohol and certain medications (e.g. methotrexate) can reduce the body's absorption of folate.