Holo-TC (Holo-Transcobalamin)
Acquire test
Visit your pharmacy and ask about CaboCheck.
With each test, you will receive an information sheet with your personal test QR code (CaboCheck-ID), through which you can retrieve the test result.
Test execution on-site or at a later date
You have the choice to have the test done directly in the pharmacy or to make an appointment. Sample collection is done quickly and easily by our special capillary blood machine, which ensures a gentle and efficient blood draw.
Quick and reliable results
Your sample will be evaluated by a professional laboratory, and you will receive your detailed laboratory report via email within 2-3 days. Benefit from the accuracy and reliability of medical laboratory tests, conveniently and easily conducted in your pharmacy.
CaboCheck Benefits
Professionelle Probenentnahme vor Ort in der Apotheke
Einfache Kapillarblutentnahme innerhalb von 2 Minuten
Auswertung durch medizinisches Facharztlabor
Labor-Ergebnisse als PDF oder online
Fragen und Antworten zu Holotranscobalamin
What is the respective laboratory value?
Holo-Transcobalamin (Holo-TC) is the biologically active form of vitamin B12 that is bound to the transport protein Transcobalamin. The laboratory value measures the concentration of Holo-TC in the blood and provides early indications of a functional vitamin B12 deficiency.
For whom is such a test to be considered?
A Holo-TC test is recommended for: People with non-specific symptoms such as fatigue, memory disorders or neurological complaints Patients with a normal or borderline vitamin B12 level, in whom a deficiency is suspected Persons with risk factors for vitamin B12 deficiency (e.g. vegans, elderly people) Patients with suspected pernicious anemia or malabsorption disorders
What is it used for?
The test serves for the early detection of a vitamin B12 deficiency, before severe symptoms develop. It complements the classic vitamin B12 measurement and is particularly helpful in diagnosing functional deficiencies.
What can be inferred from that?
A low holo-TC value indicates a functional vitamin B12 deficiency, which can occur despite a normal serum B12 value. Symptoms are: Fatigue and concentration problems Tingling or numbness in the extremities Anemia or neurological disorders A normal value usually excludes a deficiency and makes further tests unnecessary.
What is the ideal time for a test?
The test is meaningful in case of non-specific complaints or in risk groups such as vegans and elderly people. Testing is also appropriate in case of suspected malabsorption or before starting supplementation.
Particularly interesting?
Here is the translation: Holo-TC is a more sensitive marker than total cobalamin, as it only measures the biologically active form of vitamin B12. Alcohol abuse and medications can affect the Holo-TC level.