TRAP-5b, Ostase
Knochen-Vital Check
Acquire test
Visit your pharmacy and ask about CaboCheck.
With each test, you will receive an information sheet with your personal test QR code (CaboCheck-ID), through which you can retrieve the test result.
Test execution on-site or at a later date
You have the choice to have the test done directly in the pharmacy or to make an appointment. Sample collection is done quickly and easily by our special capillary blood machine, which ensures a gentle and efficient blood draw.
Quick and reliable results
Your sample will be evaluated by a professional laboratory, and you will receive your detailed laboratory report via email within 2-3 days. Benefit from the accuracy and reliability of medical laboratory tests, conveniently and easily conducted in your pharmacy.
CaboCheck Benefits
Professionelle Probenentnahme vor Ort in der Apotheke
Einfache Kapillarblutentnahme innerhalb von 2 Minuten
Auswertung durch medizinisches Facharztlabor
Labor-Ergebnisse als PDF oder online
Fragen und Antworten zu Ostase
What is the respective laboratory value?
Ostase is an isoenzyme of alkaline phosphatase (ALP) that is specific to bone-forming cells (osteoblasts). The laboratory value measures the concentration of Ostase in the blood and is used to assess bone metabolism.
For whom is such a test to be considered?
A test for bone metabolism is recommended for: • Patients with suspected osteoporosis or other bone metabolism disorders • Monitoring of patients under osteoporosis therapy (e.g. bisphosphonates) • People with symptoms such as bone pain or repeated fractures • Diagnosis of Paget's disease or other bone diseases • Children with suspected growth disorders
What is it used for?
The test serves the diagnosis and monitoring of diseases associated with increased or decreased bone formation. It is also used to evaluate the effectiveness of osteoporosis therapies.
What can be inferred from that?
An elevated Ostase value indicates: • Osteoporosis with increased bone resorption • Paget's disease or other bone diseases • Increased bone formation after fractures or growth spurts A low value rarely has clinical significance. Symptoms with elevated values can be: • Bone pain or increased fractures • Deformities in bone diseases such as Paget's
What is the ideal time for a test?
The testing can be carried out at any time of the day and is independent of food intake.
Particularly interesting?
• Ostase is more specific for bone metabolism than total ALP and is particularly suitable for monitoring the course of osteoporosis therapies. • Physiologically elevated values occur in children and adolescents during growth. • Chronic diseases such as liver diseases should be excluded in order to better classify the cause of an elevated ALP value.
Fragen und Antworten zu TRAP 5b
What is the respective laboratory value?
TRAP 5b is an enzyme that is specifically released by osteoclasts (bone-resorbing cells). The laboratory value measures the concentration of TRAP 5b in the blood and is used to assess bone resorption.
For whom is such a test to be considered?
A TRAP-5b test is recommended for: • Patients with suspected osteoporosis or increased bone resorption • Diagnosis of bone diseases such as Paget's disease or bone metastases • Monitoring of patients under antiresorptive therapy (e.g. bisphosphonates) • People with symptoms such as frequent fractures or bone pain
What is it used for?
The test serves the diagnosis and monitoring of diseases associated with increased bone loss. It helps to assess the activity of osteoclasts.
What can be inferred from that?
A high TRAP-5b value indicates: • Increased bone resorption in osteoporosis • Bone damage from tumors or metastases • Hyperparathyroidism with increased bone metabolism A low value indicates reduced bone resorption, which can occur with successful therapy or low metabolism. Symptoms with elevated values can include: • Bone pain • Frequent fractures
What is the ideal time for a test?
The testing can be carried out at any time of the day, but ideally at constant time points during follow-up checks.
Particularly interesting?
• TRAP 5b is a specific marker for osteoclast activity and therefore particularly useful for assessing bone resorption. • In children and adolescents during growth, elevated values can be physiological. • Diseases such as renal insufficiency can influence the values, which is why they should be interpreted in the context of other markers.