Leber-Vital Check

GGT is an enzyme that occurs in the liver, bile ducts, and kidneys. The laboratory value measures the GGT concentration in the blood and is used to assess liver and bile duct diseases.

A GGT test is recommended for: • People with symptoms such as fatigue, jaundice or pain in the right upper abdomen • Patients with suspected liver or biliary tract diseases (e.g. hepatitis, bile duct obstruction) • People with suspected alcohol abuse • Monitoring of patients with known liver diseases

The test serves to diagnose liver and biliary tract diseases, to monitor liver damage caused by alcohol or medication, and to clarify unclear upper abdominal complaints.

Here is the translation: An elevated GGT value can indicate the following conditions: • Chronic alcohol abuse • Liver diseases such as hepatitis or fatty liver • Bile duct obstruction (cholestasis) Symptoms of elevated GGT can include: • Jaundice or itching • Fatigue or weakness A low GGT value is unremarkable.

The testing can be carried out at any time of the day. Alcohol and high-fat foods should be avoided before the testing, as they can temporarily increase the values.

• GGT is a sensitive but non-specific marker for liver diseases and should always be interpreted in combination with other liver values such as ALT and AST. • Chronic alcohol abuse often significantly increases GGT, which is used in addiction medicine to monitor the course of the disease. • Certain medications such as anticonvulsants or statins can influence the GGT value.

Here is the translation: ALT is an enzyme that is mainly found in the liver. The laboratory value measures the concentration of ALT in the blood and is used to assess liver function and detect liver damage.

An ALT test is recommended for: Persons with symptoms such as fatigue, jaundice or abdominal pain Patients at risk of liver damage (e.g. due to alcohol abuse, hepatitis infections, medications) Monitoring of patients with known liver diseases Preventive examination in case of increased risk of fatty liver (e.g. overweight, diabetes)

The test serves the diagnosis and monitoring of liver diseases such as hepatitis, fatty liver or cirrhosis. It helps to clarify the cause of unclear complaints and to detect liver damage at an early stage.

An elevated ALT value indicates damage to the liver cells, as in: Acute or chronic hepatitis Alcohol-induced liver damage Drug-induced liver damage Symptoms with elevated ALT can be: Fatigue, loss of appetite Jaundice, dark urine A low ALT value usually has no clinical significance.

The testing can be carried out at any time of the day.

OLD is more specific for the liver than other liver enzymes like AST. An isolated increase in OLD usually requires further diagnostic tests such as ultrasound or virus serology. Chronically elevated OLD values can be an indication of non-alcoholic fatty liver disease.

AST is an enzyme that occurs in various tissues, especially in the liver, in the heart muscle and in the muscles. The laboratory value measures the concentration of AST in the blood and is used to assess liver and heart function as well as muscle damage.

A AST test is recommended for: • Persons with suspected liver damage or liver diseases (e.g. hepatitis, cirrhosis of the liver) • Patients with symptoms such as jaundice, fatigue or pain in the upper abdomen • People with suspected heart attack or muscle damage • Monitoring of patients with known liver or heart problems

The test serves the diagnosis and monitoring of diseases that are associated with cell damage in the liver, heart or muscles. It is often measured together with ALT to distinguish between liver and heart problems.

Here is the translation: An elevated AST value can indicate the following conditions: • Liver damage due to hepatitis, alcohol abuse or medication • Heart attack • Muscle diseases such as myositis or muscular dystrophy A low value is unremarkable and has no clinical significance. Symptoms of elevated AST can include: • Jaundice or dark urine in liver problems • Chest pain or shortness of breath in heart problems • Muscle pain or weakness in muscle diseases

The testing can be carried out at any time of the day.

• AST is less specific for the liver than ALT, as it occurs in many tissues. • The ratio of AST to ALT (De-Ritis ratio) can help distinguish between alcoholic and non-alcoholic liver damage. • Muscle injuries or strenuous physical exertion can also increase AST.