Vitamin B1

Vitamin B1, also called Thiamine, is a water-soluble vitamin that primarily acts in the body in its active form as Thiamine Pyrophosphate (TPP). In the blood, it is predominantly found in the red blood cells (erythrocytes), with only a small portion in the plasma. The laboratory value indicates the total amount of Thiamine present in the whole blood, usually measured as Thiamine or TPP.

The test is meaningful for people who have an increased risk of vitamin B1 deficiency. This includes primarily customers with chronic alcohol abuse, malnutrition, malabsorption disorders, people on parenteral nutrition, pregnant and breastfeeding women, as well as people with liver disease or dialysis. Even if neurological symptoms such as fatigue, irritability or loss of appetite exist, the B1 value can provide information.

The value is required to assess the supply status of vitamin B1. In case of suspected deficiency, it can help determine whether there is actually an undersupply. Additionally, the test can be used to monitor the success of thiamine administration in high-risk groups.

A low value indicates a possible deficiency - this can explain why someone, for example, quickly becomes tired or shows neurological symptoms. A normal value, on the other hand, suggests that the supply with regard to vitamin B1 is sufficient. High values are rarely clinically relevant, as excess thiamine is easily excreted through the kidneys, unless there is a severe interfering factor.

A specific "day" in the course of the disease is not required - because it is about the general care. The test is particularly appropriate if symptoms occur or risk factors exist. It can also be useful shortly after risk factors have been eliminated or thiamin has been supplemented (e.g. after or during a treatment) to check the effect.